Borderline low testosterone deficiency (12-15 nmol/L)
Reduced sex drive and an increased occurrence of erectile dysfunction.
A decrease in muscle mass and strength, and a generally lower threshold of tolerance to exercise.
Mild testosterone deficiency (10-12 nmol/L)
Moderate testosterone deficiency (8-10 nmol/L)
Mood fluctuations with an increased risk of depression and anxiety.
Difficulties sleeping, including more frequent awakenings and finding it more difficult to get to and stay asleep.
Brain fog and a lack of ability to concentrate or focus.
Further weight increases and heightened risk of developing type 2 diabetes.
Lower bone mineral density, which increases the risk of osteoporosis and fractures.
Severe testosterone deficiency (<8 nmol/L)
Significant decrease in libido, frequent erectile dysfunction, and risk of infertility.
Hot flushes.
Increased risk of lower urinary tract symptoms, particularly in those with type 2 diabetes.
Increased risk of arterial hypertension (higher blood pressure), especially in those who smoke and/or are obese.
More pronounced mood swings with severe depression and emotional instability.
Zitzmann, M., Faber, S., & Nieschlag, E. (2006). Association of specific symptoms and metabolic risks with serum testosterone in older men. The Journal of Clinical Endocrinology and Metabolism, 91(11), 4335–4343. doi:10.1210/jc.2006-0401
Shigehara, K., Izumi, K., Kadono, Y., & Mizokami, A. (2021). Testosterone and bone health in men: A narrative review. Journal of Clinical Medicine, 10(3), 530. doi:10.3390/jcm10030530