weight loss
∙5 minute read
Switching from one weight loss medication to another can feel a bit daunting. If you’re moving from Mounjaro to Wegovy, you might worry about setbacks, side effects, or whether your progress will stall.
But you’ve already done the hard part. You’ve built a strong foundation by committing to your health, and with the right approach, you can keep moving forward confidently.
Weight loss isn’t just about the injection you take each week. It’s about the habits, routines, and support systems you build around it. Below are some practical tips to help you stay on track during your switch.
Medication helps with appetite and cravings, but movement is what keeps your body strong, energised, and resilient. The NHS recommends at least 150 minutes of moderate activity per week, which can sound like a lot, but it’s just over 20 minutes a day.1
Simple ways to hit your goal:
Brisk walking or cycling to work.
Taking the stairs instead of the lift.
Joining a class you enjoy (boxing, yoga, swimming, whatever feels fun).
Dancing in your living room.
Add in a couple of strength training sessions each week. Building muscle not only makes you stronger but also helps your body burn more calories, even while resting.2
Mounjaro and Wegovy both work by helping you feel fuller, but what you choose to eat still makes all the difference. A healthy, balanced diet supports your medication and makes weight loss sustainable.
Try to focus on:
Fibre-rich foods: (fruit, vegetables, beans, wholegrains) to keep you fuller for longer and support gut health.
Protein at every meal: (lean meats, fish, eggs, tofu, legumes) to protect muscle mass while you lose weight.
Nutritionally balanced meals: a mix of carbs, healthy fats, and protein, so you feel energised rather than deprived.
Reducing processed foods and added sugars: these can cause energy dips and cravings.
Think of food as fuel - the better quality you give your body, the smoother your journey will be.
Having someone to guide you makes a huge difference. A health coach can help you set realistic goals, track your progress, and troubleshoot challenges like cravings or energy slumps. If you don’t have access to a coach, try creating your own accountability system:
Share your goals with a friend.
Track meals, workouts, and moods in an app or journal.
Celebrate small wins along the way (they add up).
Weight loss is rarely a straight line. Switching from Mounjaro to Wegovy may feel different at first, and anecdotal evidence suggests that some people might notice temporary weight fluctuations. That doesn’t mean you’re failing. Your body is just adjusting.
What matters most is consistency. If you slip up, skip a workout, or overeat one day, don’t beat yourself up. Nothing is “ruined.” Every step forward counts.
These medications aren’t quick fixes; they’re tools to help you make lasting lifestyle changes. Over time, it’s the combination of healthy eating, regular movement, adhering to medication, and ongoing support that drives the best results.
Switching treatments may feel like a bump in the road, but it doesn’t erase your progress. You’ve already proven you can commit to yourself and your health. With the right mindset and habits, you’ll keep moving towards your goals.
Stay active, eat well, seek support, and be kind to yourself. With these foundations in place, your transition from Mounjaro to Wegovy can be smooth, and your weight loss journey can continue without interruption.
Website NHS. Physical activity guidelines for adults aged 19 to 64. nhs.uk. https://www.nhs.uk/live-well/exercise/physical-activity-guidelines-for-adults-aged-19-to-64/ [Accessed 20th August 2025].
McPherron AC, Guo T, Bond ND, Gavrilova O. Increasing muscle mass to improve metabolism. Adipocyte. 2013;2(2): 92–98.
Written by Hassan Thwaini
Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm)
